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Database Appeal. Unique urgently needs to raise £30,000 to replace our old database to create a new more powerful patient registry to increase our knowledge and understanding of the lifelong impacts on children and adults with rare chromosome & gene disorders and encourage research. Please click to donate today.. Trippie bri rare condition

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Stiff person syndrome (SPS) is a rare acquired neurological disorder that most often causes progressive muscle stiffness (rigidity) and repeated episodes of painful muscle spasms. Muscular rigidity often fluctuates (i.e., grows worse and then improves) and usually occurs along with the muscle spasms.Some children also have slowing of head growth (acquired microcephaly), Affected children often develop autistic-like behaviors, breathing irregularities, feeding and swallowing difficulties, growth retardation, and seizures. Most Rett syndrome cases are caused by identifiable mutations of the MECP2 gene on the X chromosome and can …Progress in 2022. The 2022 action plan announced £40m in funding for the NIHR BioResource, which is supporting research using genetic information to find new tests and treatments for rare diseases. 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